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In INS-1E cells, silencing of the malate/aspartate transporter Aralar1 in the mitochondrial inner membrane that is necessary for the malate/aspartate shuttle partly impairs GSIS [27], further suggesting a role for the malate/aspartate shuttle in GSIS
Step 3: Submit Prior Authorization Your healthcare provider will need to complete prior authorization documentation and send it in for Aetna to cover tirzepatide (Zepbound)
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